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dc.contributor.authorAćimović, Milica
dc.contributor.authorPezo, Lato
dc.contributor.authorČabarkapa, Ivana
dc.contributor.authorAnika, Trudić
dc.contributor.authorJeremić Stanković, Jovana
dc.contributor.authorVarga, Ana
dc.contributor.authorBiljana, Lončar
dc.contributor.authorŠovljanski, Olja
dc.contributor.authorTešević, Vele
dc.date.accessioned2023-07-15T00:18:38Z
dc.date.available2023-07-15T00:18:38Z
dc.date.issued2022-08-14
dc.identifier.citationAćmović, M.; Pezo, L.; Čabarkapa, I.; Trudić, A.; Stanković, Jeremić, J.; Varga, A.; Lončar, B.; Šovljanski, O.; Tešević,V. Variation of Salvia officinalis L. Essential Oil and Hydrolate Composition and Their Antimicrobial Activity. Processes 2022, 10, 1608. https://doi.org/10.3390/ pr10081608en_US
dc.identifier.issn2227-9717
dc.identifier.urihttp://oa.fins.uns.ac.rs/handle/123456789/275
dc.description.abstractThis study aimed to investigate the chemical composition of steam distillate essential oil and corresponding hydrolate obtained from S. officinalis grown in Serbia, as well as the influence of weather conditions (temperature and precipitations) on their chemical profiles. Furthermore, their antimicrobial activity was investigated in vitro. The main compounds in essential oil were cis-thujone, followed by camphor, trans-thujone, and 1,8-cineole, while hydrolate was slightly different from the essential oil, with camphor, cis-thujone, and 1,8-cineole as the main compounds. Among the eight respiratory-associated microorganisms, Klebsiella oxytoca was the most sensitive to the tested EOs (minimum inhibitory concentration (MIC)/minimal bactericidal/fungicidal concentration (MBC/MFC) were 14.20 and 28.4 μL mL−1, respectively). MIC and MBC values of other tested bacteria ranged between 28.40 and 227.25 μL mL−1 while for Candida albicans MIC/MFC ranged from 28.40/56.81 to 56.81–113.63 μL mL−1. Antibiotic susceptibility patterns for the analyzed eight respiratory-associated microorganisms showed an intermediate level of resistance to commonly used antibiotics such as ampicillin, levofloxacin, and ciprofloxacin. As a preliminary approach to the antimicrobial profiling of the tested EO, the obtained results revealed that the tested samples possess remarkable antibacterial activities and could be used to develop pharmaceutical formulations as an alternative to conventional antibiotic therapy.en_US
dc.language.isoenen_US
dc.publisherMDPIen_US
dc.relationinfo:eu-repo/grantAgreement/MESTD/inst-2021/200051/RS// info:eu-repo/grantAgreement/MESTD/inst-2021/200012/RS// info:eu-repo/grantAgreement/MESTD/inst-2021/200132/RS// info:eu-repo/grantAgreement/MESTD/inst-2022/200134/RS// info:eu-repo/grantAgreement/MESTD/inst-2021/200134/RS// info:eu-repo/grantAgreement/MESTD/inst-2021/200125/RS// info:eu-repo/grantAgreement/MESTD/inst-2021/200126/RS//
dc.rightsopenAccess
dc.subjectSalvia officinalisen_US
dc.subjectessential oilen_US
dc.subjectweather conditionsen_US
dc.subjecthydrolateen_US
dc.subjectantimicrobial activityen_US
dc.subjectin vitroen_US
dc.titleVariation of Salvia officinalis L. Essential Oil and Hydrolate Composition and Their Antimicrobial Activityen_US
dc.typeArticleen_US
dc.typeinfo:eu-repo/semantics/article
dc.identifier.scopus2-s2.0-85137589816
dc.identifier.wos000845774600001


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